| Dear Dr Wirawan,
We are pleased to share with you our June content update, featuring journal news, top articles and our most recent table of contents. From the BMC Medicine blog | | BMC Medicine publishes an article investigating a system intervention to improve the quality of life for patients with multiple complex problems in Scotland. This study, known as CARE Plus, also looks at the cost-effectiveness of the intervention and finds some promising results. Co-author Stewart Mercer explains more here. | | | Here, Dr David MacIntyre and Prof Phillip Bennett, co-authors of an article published in BMC Medicine, explain more about their research on modeling hormonal and inflammatory contributions to preterm and term labor. | Table of Contents Commentary Guideline Minireview Opinion Beyond viral suppression of HIV – the new quality of life frontier | Jeffrey V. Lazarus, Kelly Safreed-Harmon, Simon E. Barton, Dominique Costagliola, Nikos Dedes, Julia del Amo Valero, Jose M. Gatell, Ricardo Baptista-Leite, Luís Mendão, Kholoud Porter, Stefano Vella and Jürgen Kurt Rockstroh | BMC Medicine 2016, 14:94 | Question and Answer Research Modifiable causes of premature death in middle-age in Western Europe: results from the EPIC cohort study | David C. Muller, Neil Murphy, Mattias Johansson, Pietro Ferrari, Konstantinos K. Tsilidis, Marie-Christine Boutron-Ruault, Francoise Clavel, Laureen Dartois, Kuanrong Li, Rudolf Kaaks, Cornelia Weikert, Manuela Bergmann, Heiner Boeing, Anne Tjønneland, Kim Overvad, M. Luisa Redondo... | BMC Medicine 2016, 14:87 | The CARE Plus study – a whole-system intervention to improve quality of life of primary care patients with multimorbidity in areas of high socioeconomic deprivation: exploratory cluster randomised controlled trial and cost-utility analysis | Stewart W. Mercer, Bridie Fitzpatrick, Bruce Guthrie, Elisabeth Fenwick, Eleanor Grieve, Kenny Lawson, Nicki Boyer, Alex McConnachie, Suzanne M. Lloyd, Rosaleen O'Brien, Graham C. M. Watt and Sally Wyke | BMC Medicine 2016, 14:88 | Modeling the spread of polio in an IPV-vaccinated population: lessons learned from the 2013 silent outbreak in southern Israel | Rami Yaari, Ehud Kaliner, Itamar Grotto, Guy Katriel, Jacob Moran-Gilad, Danit Sofer, Ella Mendelson, Elizabeth Miller, Amit Huppert, E. Anis, E. Kopel, Y. Manor, O. Mor, L. Shulman, R. Singer and M. Weil | BMC Medicine 2016, 14:95 | No effects of oral vitamin D supplementation on non-alcoholic fatty liver disease in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial | Ilaria Barchetta, Maria Del Ben, Francesco Angelico, Michele Di Martino, Antonio Fraioli, Giuseppe La Torre, Rosella Saulle, Ludovica Perri, Sergio Morini, Claudio Tiberti, Laura Bertoccini, Flavia Agata Cimini, Francesca Panimolle, Carlo Catalano, Marco Giorgio Baroni and Maria Gisella Cavallo | BMC Medicine 2016, 14:92 | Review Benefits of Publishing with Us • | 2015 median turnover times: initial decision three days; first decision after peer review 40 days | • | Portable peer review | • | Broad medical readership | Follow @BMCMedicine on Twitter | | | |