December 14, 2016

BMC Medicine monthly contents – November 2016

 
BMC Medicine
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Dear Dr Wirawan,

We are pleased to share with you our November content update, featuring journal news, top articles and our most recent table of contents.



From the BMC Medicine Blog

WANETAM: Preparing West Africa for large scale tuberculosis research and drug-resistance surveillance
WANETAM: Preparing West Africa for large scale tuberculosis research and drug-resistance surveillance

Published in BMC Medicine, a new collaborative study reports on the prevalence of tuberculosis drug resistance in West Africa, a previous white spot in our drug resistance knowledge. Here, three of the study's authors tell us about the challenges and achievements of one of the largest West African collaborations to date.


Update on Translational Oncology: different flavors of immunotherapy and cancer heterogeneity
Update on Translational Oncology: different flavors of immunotherapy and cancer heterogeneity

Since its launch in July this year, BMC Medicine's article collection on Translational Oncology has attracted interesting research articles. Here, we present a brief overview of the most recent publications on adoptive immunotherapy for bladder cancer, tumor-associated macrophages in classical Hodgkin lymphoma, correlating tumor mutation load with immunotherapy outcomes and spatial transcriptome analysis of glioblastoma.


40 years of cancer evolution: time to understand its clinical implications
40 years of cancer evolution: time to understand its clinical implications

Tumor heterogeneity is observed at many levels: from cancer subclones in primary tumor with distinct characteristics to differences between primary and metastatic tumors in the same individual. As it affects treatment response, it is one of the key challenges in effective cancer management in the clinical practice. Here, co-authors of an article published in BMC Medicine discuss their study of kidney cancer patients.



Table of Contents

Commentary

Inhibiting the proton pump: mechanisms, benefits, harms, and questions

Genomic profiling for copy number changes in plasma of ovarian cancer patients – a new era for cancer diagnostics?

The inevitable colonisation of Singapore by Zika virus

Alcohol and stroke: the splitters win again

A framework: make it useful to guide and improve practice of clinical trial design in smaller populations

Correspondence

How do you design randomised trials for smaller populations? A framework

Editorial

What is new in vascular dementia?

Gout: will the "King of Diseases" be the first rheumatic disease to be cured?

Forum

It's a long shot, but it just might work! Perspectives on the future of medicine

Guideline

Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppression

Opinion

Is the time ripe for new diagnostic criteria of cognitive impairment due to cerebrovascular disease? Consensus report of the International Congress on Vascular Dementia working group

Vascular depression consensus report – a critical update

Research

The emerging threat of pre-extensively drug-resistant tuberculosis in West Africa: preparing for large-scale tuberculosis research and drug resistance surveillance

Maternal urinary metabolic signatures of fetal growth and associated clinical and environmental factors in the INMA study

Renal function estimation and Cockcroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart 'OMics' in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives

Heterogeneous response and progression patterns reveal phenotypic heterogeneity of tyrosine kinase inhibitor response in metastatic renal cell carcinoma

MEN1 redefined, a clinical comparison of mutation-positive and mutation-negative patients

Prevalence, aetiology, treatment and outcomes of shock in children admitted to Kenyan hospitals

Modelling the effect of short-course multidrug-resistant tuberculosis treatment in Karakalpakstan, Uzbekistan

Physical multimorbidity and psychosis: comprehensive cross sectional analysis including 242,952 people across 48 low- and middle-income countries

Evaluation of computer-based computer tomography stratification against outcome models in connective tissue disease-related interstitial lung disease: a patient outcome study

Differing association of alcohol consumption with different stroke types: a systematic review and meta-analysis

Identifying and prioritizing lower value services from Dutch specialist guidelines and a comparison with the UK do-not-do list

Impact of a web-based tool (WebCONSORT) to improve the reporting of randomised trials: results of a randomised controlled trial

Post-marketing withdrawal of anti-obesity medicinal products because of adverse drug reactions: a systematic review

Reporting of statistically significant results at ClinicalTrials.gov for completed superiority randomized controlled trials

Review

Neuroimaging in vascular cognitive impairment: a state-of-the-art review


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