Latest Article Alert from Breast Cancer Research

The following new articles have just been published in Breast Cancer Research

For articles using Author Version-first publication you will see a provisional PDF corresponding to the accepted manuscript. In these instances, the fully formatted Final Version PDF and full text (HTML) versions will follow in due course.


Research article
Background risk of breast cancer and the association between physical activity and mammographic density
Trinh T, Eriksson M, Darabi H, Bonn SE, Brand JS, Cuzick J, Czene K, Sjölander A, Bälter K, Hall P
Breast Cancer Research 2015, 17:50 (2 April 2015)
Abstract http://breast-cancer-research.com/content/17/1/50/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0565-4.pdf

Research article
Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: a case-control study
Tikk K, Sookthai D, Fortner RT, Johnson T, Rinaldi S, Romieu I, Tjønneland A, Olsen A, Overvad K, Clavel-Chapelon F, Baglietto L, Boeing H, Trichopoulou A, Lagiou P, Trichopoulos D, Masala G, Krogh V, Tumino R, Ricceri F, Mattiello A, Agudo A, Menéndez V, Sánchez M, Amiano P, Chirlaque M, Barricarte A, Bueno-de-Mesquita H, Monninkhof EM, Onland-Moret N, Andresson A
Breast Cancer Research 2015, 17:49 (31 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/49/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0563-6.pdf

Research article
Enhanced anti-tumor immune responses and delay of tumor development in human epidermal growth factor receptor 2 mice immunized with an immunostimulatory peptide in poly(D,L-lactic-co-glycolic) acid nanoparticles nanoparticles
Campbell D, Saenz R, Bharati IS, Seible D, Zhang L, Esener S, Messmer B, Larsson M, Messmer D
Breast Cancer Research 2015, 17:48 (31 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/48/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0552-9.pdf

Research article
FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth
Tancioni I, Miller NL, Uryu S, Lawson C, Jean C, Chen X, Kleinschmidt EG, Schlaepfer DD
Breast Cancer Research 2015, 17:47 (28 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/47/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0551-x.pdf

Research article
Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy
Snyder KA, Hughes MR, Hedberg B, Brandon J, Hernaez D, Bergqvist P, Cruz F, Po K, Graves ML, Turvey ME, Nielsen JS, Wilkins JA, McColl SR, Babcook JS, Roskelley CD, McNagny KM
Breast Cancer Research 2015, 17:46 (27 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/46/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0562-7.pdf

Research article
Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases
Tabariès S, Ouellet V, Hsu BE, Annis MG, Rose A, Meunier L, Carmona E, Tam CE, Mes-Masson A, Siegel PM
Breast Cancer Research 2015, 17:45 (27 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/45/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0558-3.pdf

Research article
Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
Tinholt M, Vollan H, Sahlberg K, Jernström S, Kaveh F, Lingjærde O, Kåresen R, Sauer T, Kristensen V, Børresen-Dale A, Sandset P, Iversen N
Breast Cancer Research 2015, 17:44 (26 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/44/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0548-5.pdf

Research article
Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response
Jézéquel P, Loussouarn D, Guérin-Charbonnel C, Campion L, Vanier A, Gouraud W, Lasla H, Guette C, Valo I, Verrièle V, Campone M
Breast Cancer Research 2015, 17:43 (20 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/43/abstract
Full text http://breast-cancer-research.com/content/17/1/43
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0550-y.pdf

Research article
Mesenchymal stem cells mediate the clinical phenotype of inflammatory breast cancer in a pre-clinical model
Lacerda L, Debeb BG, Smith D, Larson R, Solley T, Xu W, Krishnamurthy S, Gong Y, Levy LB, Buchholz T, Ueno NT, Klopp A, Woodward WA
Breast Cancer Research 2015, 17:42 (20 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/42/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0549-4.pdf

Research article
Quantitative measurement of HER2 expression in breast cancers: comparison with ‘real-world’ routine HER2 testing in a multicenter Collaborative Biomarker Study and correlation with overall survival
Yardley DA, Kaufman PA, Huang W, Krekow L, Savin M, Lawler WE, Zrada S, Starr A, Einhorn H, Schwartzberg LS, Adams JW, Lie Y, Paquet AC, Sperinde J, Haddad M, Anderson S, Brigino M, Pesano R, Bates MP, Weidler J, Bosserman L
Breast Cancer Research 2015, 17:41 (18 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/41/abstract
Full text http://breast-cancer-research.com/content/17/1/41
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0543-x.pdf

Research article
Estimated dietary dioxin exposure and breast cancer risk among women from the French E3N prospective cohort
Danjou A, Fervers B, Boutron-Ruault M, Philip T, Clavel-Chapelon F, Dossus L
Breast Cancer Research 2015, 17:39 (17 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/39/abstract
Full text http://breast-cancer-research.com/content/17/1/39
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0536-9.pdf

Review
Mechanisms of endocrine resistance in breast cancer: an overview of the proposed roles of noncoding RNA
Hayes EL, Lewis-Wambi JS
Breast Cancer Research 2015, 17:40 (17 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/40/abstract
Full text http://breast-cancer-research.com/content/17/1/40
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0542-y.pdf

Research article
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Decock J, Hendrickx W, Thirkettle S, Gutiérrez-Fernández A, Robinson SD, Edwards DR
Breast Cancer Research 2015, 17:38 (14 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/38/abstract
Full text http://breast-cancer-research.com/content/17/1/38
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0545-8.pdf

Review
Lobular breast cancer: incidence and genetic and non-genetic risk factors
Dossus L, Benusiglio PR
Breast Cancer Research 2015, 17:37 (13 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/37/abstract
Full text http://breast-cancer-research.com/content/17/1/37
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0546-7.pdf

Research article
Lectin RCA-I specifically binds to metastasis-associated cell surface glycans in triple-negative breast cancer
Zhou S, Cheng L, Guo S, Wang Y, Czajkowsky DM, Gao H, Hu X, Tao S
Breast Cancer Research 2015, 17:36 (11 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/36/abstract
Full text http://breast-cancer-research.com/content/17/1/36
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0544-9.pdf

Research article
Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer
López-Knowles E, Wilkerson PM, Ribas R, Anderson H, Mackay A, Ghazoui Z, Rani A, Osin P, Nerurkar A, Renshaw L, Larionov A, Miller WR, Dixon J, Reis-Filho JS, Dunbier AK, Martin L, Dowsett M
Breast Cancer Research 2015, 17:35 (11 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/35/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0532-0.pdf

Research article
Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients
Bailur J, Gueckel B, Derhovanessian E, Pawelec G
Breast Cancer Research 2015, 17:34 (10 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/34/abstract
Full text http://breast-cancer-research.com/content/17/1/34
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0541-z.pdf

Research article
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells
Min A, Im S, Kim D, Song S, Kim H, Lee K, Kim T, Han S, Oh D, Kim T, O’Connor MJ, Bang Y
Breast Cancer Research 2015, 17:33 (7 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/33/abstract
Provisional PDF http://breast-cancer-research.com/content/pdf/s13058-015-0534-y.pdf

Research article
Mouse mammary stem cells express prognostic markers for triple-negative breast cancer
Soady KJ, Kendrick H, Gao Q, Tutt A, Zvelebil M, Ordonez LD, Quist J, Tan D, Isacke CM, Grigoriadis A, Smalley MJ
Breast Cancer Research 2015, 17:31 (4 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/31/abstract
Full text http://breast-cancer-research.com/content/17/1/31
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0539-6.pdf

Research article
Changes in insulin receptor signaling underlie neoadjuvant metformin administration in breast cancer: a prospective window of opportunity neoadjuvant study
Dowling R, Niraula S, Chang MC, Done SJ, Ennis M, McCready DR, Leong WL, Escallon JM, Reedijk M, Goodwin PJ, Stambolic V
Breast Cancer Research 2015, 17:32 (3 March 2015)
Abstract http://breast-cancer-research.com/content/17/1/32/abstract
Full text http://breast-cancer-research.com/content/17/1/32
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0540-0.pdf

Research article
FOXF2 deficiency promotes epithelial-mesenchymal transition and metastasis of basal-like breast cancer
Wang Q, Kong P, Li X, Yang F, Feng Y
Breast Cancer Research 2015, 17:30 (26 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/30/abstract
Full text http://breast-cancer-research.com/content/17/1/30
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0531-1.pdf

Research article
Molecular subtyping for clinically defined breast cancer subgroups
Zhao X, Rødland E, Tibshirani R, Plevritis S
Breast Cancer Research 2015, 17:29 (26 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/29/abstract
Full text http://breast-cancer-research.com/content/17/1/29
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0520-4.pdf

Research article
Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models
Li Y, Drabsch Y, Pujuguet P, Ren J, van Laar T, Zhang L, van Dam H, Clément-Lacroix P, ten Dijke P
Breast Cancer Research 2015, 17:28 (25 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/28/abstract
Full text http://breast-cancer-research.com/content/17/1/28
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0537-8.pdf

Research article
In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α
Singh K, Munuganti R, Leblanc E, Lin Y, Leung E, Lallous N, Butler M, Cherkasov A, Rennie PS
Breast Cancer Research 2015, 17:27 (25 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/27/abstract
Full text http://breast-cancer-research.com/content/17/1/27
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0529-8.pdf

Research article
Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression
Raha P, Thomas S, Thurn K, Park J, Munster PN
Breast Cancer Research 2015, 17:26 (25 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/26/abstract
Full text http://breast-cancer-research.com/content/17/1/26
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0533-z.pdf

Research article
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer
Granados-Principal S, Liu Y, Guevara ML, Blanco E, Choi D, Qian W, Patel T, Rodriguez AA, Cusimano J, Weiss HL, Zhao H, Landis MD, Dave B, Gross SS, Chang JC
Breast Cancer Research 2015, 17:25 (22 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/25/abstract
Full text http://breast-cancer-research.com/content/17/1/25
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0527-x.pdf

Research article
RANK-ligand (RANKL) expression in young breast cancer patients and during pregnancy
Azim HA, Peccatori FA, Brohée S, Branstetter D, Loi S, Viale G, Piccart M, Dougall WC, Pruneri G, Sotiriou C
Breast Cancer Research 2015, 17:24 (21 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/24/abstract
Full text http://breast-cancer-research.com/content/17/1/24
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0538-7.pdf

Research article
Prognostic stromal gene signatures in breast cancer
Winslow S, Leandersson K, Edsjö A, Larsson C
Breast Cancer Research 2015, 17:23 (21 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/23/abstract
Full text http://breast-cancer-research.com/content/17/1/23
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0530-2.pdf

Research article
A case–control analysis of oral contraceptive use and breast cancer subtypes in the African American Breast Cancer Epidemiology and Risk Consortium
Bethea TN, Rosenberg L, Hong C, Troester MA, Lunetta KL, Bandera EV, Schedin P, Kolonel LN, Olshan AF, Ambrosone CB, Palmer JR
Breast Cancer Research 2015, 17:22 (21 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/22/abstract
Full text http://breast-cancer-research.com/content/17/1/22
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0535-x.pdf

Research article
Mammary gland tumor promotion by chronic administration of IGF1 and the insulin analogue AspB10 in the p53R270H/+WAPCre mouse model
ter Braak B, Siezen C, Speksnijder EN, Koedoot E, van Steeg H, Salvatori D, van de Water B, van der Laan J
Breast Cancer Research 2015, 17:14 (18 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/14/abstract
Full text http://breast-cancer-research.com/content/17/1/14
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0518-y.pdf

Review
Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management
van Schooneveld E, Wildiers H, Vergote I, Vermeulen PB, Dirix LY, Van Laere SJ
Breast Cancer Research 2015, 17:21 (18 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/21/abstract
Full text http://breast-cancer-research.com/content/17/1/21
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0526-y.pdf

Research article
Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth
Ren X, Wang J, Osada T, Mook RA, Morse MA, Barak LS, Lyerly H, Chen W
Breast Cancer Research 2015, 17:20 (15 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/20/abstract
Full text http://breast-cancer-research.com/content/17/1/20
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0528-9.pdf

Research article
Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy
Kren BT, Unger GM, Abedin MJ, Vogel RI, Henzler CM, Ahmed K, Trembley JH
Breast Cancer Research 2015, 17:19 (11 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/19/abstract
Full text http://breast-cancer-research.com/content/17/1/19
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0524-0.pdf
PubMed http://breast-cancer-research.com/pubmed/25837326

Research article
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy
Lei J, Rudolph A, Moysich KB, Rafiq S, Behrens S, Chang-Claude J, kConFab Investigators
Breast Cancer Research 2015, 17:18 (10 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/18/abstract
Full text http://breast-cancer-research.com/content/17/1/18
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0522-2.pdf

Review
Patient-derived xenograft models of breast cancer and their predictive power
Whittle JR, Lewis MT, Lindeman GJ, Visvader JE
Breast Cancer Research 2015, 17:17 (10 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/17/abstract
Full text http://breast-cancer-research.com/content/17/1/17
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0523-1.pdf

Review
Lobular breast cancer: molecular basis, mouse and cellular models
Christgen M, Derksen P
Breast Cancer Research 2015, 17:16 (8 February 2015)
Abstract http://breast-cancer-research.com/content/17/1/16/abstract
Full text http://breast-cancer-research.com/content/17/1/16
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0517-z.pdf
PubMed http://breast-cancer-research.com/pubmed/25757734

Research article
Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
Bhoo-Pathy N, Peeters P, Uiterwaal C, Bueno-de-Mesquita H, Bulgiba AM, Bech B, Overvad K, Tjønneland A, Olsen A, Clavel-Chapelon F, Fagherazzi G, Perquier F, Teucher B, Kaaks R, Schütze M, Boeing H, Lagiou P, Orfanos P, Trichopoulou A, Agnoli C, Mattiello A, Palli D, Tumino R, Sacerdote C, van Duijnhoven F, Braaten T, Lund E, Skeie G, Redondo M, Buckland G
Breast Cancer Research 2015, 17:15 (31 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/15/abstract
Full text http://breast-cancer-research.com/content/17/1/15
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0521-3.pdf

Research article
MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer
Vilquin P, Donini CF, Villedieu M, Grisard E, Corbo L, Bachelot T, Vendrell JA, Cohen PA
Breast Cancer Research 2015, 17:13 (30 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/13/abstract
Full text http://breast-cancer-research.com/content/17/1/13
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0515-1.pdf
PubMed http://breast-cancer-research.com/pubmed/25633049

Review
Invasive lobular carcinoma of the breast: morphology, biomarkers and ’omics
Reed AE, Kutasovic JR, Lakhani SR, Simpson PT
Breast Cancer Research 2015, 17:12 (30 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/12/abstract
Full text http://breast-cancer-research.com/content/17/1/12
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0519-x.pdf

Review
Multigene prognostic tests in breast cancer: past, present, future
Győrffy B, Hatzis C, Sanft T, Hofstatter E, Aktas B, Pusztai L
Breast Cancer Research 2015, 17:11 (27 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/11/abstract
Full text http://breast-cancer-research.com/content/17/1/11
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0514-2.pdf

Review
Markers for the identification of late breast cancer recurrence
Sestak I, Cuzick J
Breast Cancer Research 2015, 17:10 (27 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/10/abstract
Full text http://breast-cancer-research.com/content/17/1/10
PDF http://breast-cancer-research.com/content/pdf/s13058-015-0516-0.pdf

Erratum
Erratum to: “A novel role for ezrin in breast cancer angio/lymphangiogenesis”
Ghaffari A, Hoskin V, Szeto A, Hum M, Liaghati N, Nakatsu K, LeBrun D, Madarnas Y, SenGupta S, Elliott BE
Breast Cancer Research 2015, 17:9 (23 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/9/abstract
Full text http://breast-cancer-research.com/content/17/1/9
PDF http://breast-cancer-research.com/content/pdf/s13058-014-0511-x.pdf

Review
Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer
Harris RS
Breast Cancer Research 2015, 17:8 (21 January 2015)
Abstract http://breast-cancer-research.com/content/17/1/8/abstract
Full text http://breast-cancer-research.com/content/17/1/8
PDF http://breast-cancer-research.com/content/pdf/s13058-014-0498-3.pdf








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