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Research
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
Decker J, Krüger L, Sydow A, Zhao S, Frotscher M, Mandelkow E, Mandelkow E
Acta Neuropathologica Communications 2015, 3:23 (3 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/23/abstract
Full text http://www.actaneurocomms.org/content/3/1/23
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0193-3.pdf

Research
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T
Acta Neuropathologica Communications 2015, 3:22 (3 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/22/abstract
Full text http://www.actaneurocomms.org/content/3/1/22
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0201-7.pdf

Research
Ability of wild type mouse bioassay to detect bovine spongiform encephalopathy (BSE) in the presence of excess scrapie
Corda E, Thorne L, Beck KE, Lockey R, Green RB, Vickery CM, Holder TM, Terry LA, Simmons MM, Spiropoulos J
Acta Neuropathologica Communications 2015, 3:21 (3 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/21/abstract
Full text http://www.actaneurocomms.org/content/3/1/21
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0194-2.pdf

Research
IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity
Kocur M, Schneider R, Pulm A, Bauer J, Kropp S, Gliem M, Ingwersen J, Goebels N, Alferink J, Prozorovski T, Aktas O, Scheu S
Acta Neuropathologica Communications 2015, 3:20 (3 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/20/abstract
Full text http://www.actaneurocomms.org/content/3/1/20
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0192-4.pdf

Research
A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques
Moreno F, Rabinovici GD, Karydas A, Miller Z, Hsu S, Legati A, Fong J, Schonhaut D, Esselmann H, Watson C, Stephens ML, Kramer J, Wiltfang J, Seeley WW, Miller BL, Coppola G, Grinberg L
Acta Neuropathologica Communications 2015, 3:19 (3 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/19/abstract
Full text http://www.actaneurocomms.org/content/3/1/19
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0190-6.pdf

Research
Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases
Torrent J, Vilchez-Acosta A, Muñoz-Torrero D, Trovaslet M, Nachon F, Chatonnet A, Grznarova K, Acquatella-Tran Van Ba I, Le Goffic R, Herzog L, Béringue V, Rezaei H
Acta Neuropathologica Communications 2015, 3:18 (3 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/18/abstract
Full text http://www.actaneurocomms.org/content/3/1/18
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0188-0.pdf

Research
Epileptogenic but MRI-normal perituberal tissue in Tuberous Sclerosis Complex contains tuber-specific abnormalities
Sosunov AA, McGovern RA, Mikell CB, Wu X, Coughlin DG, Crino PB, Weiner HL, Ghatan S, Goldman JE, McKhann GM
Acta Neuropathologica Communications 2015, 3:17 (2 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/17/abstract
Full text http://www.actaneurocomms.org/content/3/1/17
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0191-5.pdf

Research
PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein
Ciron C, Zheng L, Bobela W, Knott GW, Leone TC, Kelly DP, Schneider BL
Acta Neuropathologica Communications 2015, 3:16 (1 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/16/abstract
Full text http://www.actaneurocomms.org/content/3/1/16
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0200-8.pdf

Review
TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies
Goossens J, Vanmechelen E, Trojanowski JQ, Lee V, Van Broeckhoven C, van der Zee J, Engelborghs S
Acta Neuropathologica Communications 2015, 3:15 (1 April 2015)
Abstract http://www.actaneurocomms.org/content/3/1/15/abstract
Full text http://www.actaneurocomms.org/content/3/1/15
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0195-1.pdf

Research
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease
Pooler AM, Polydoro M, Maury EA, Nicholls SB, Reddy SM, Wegmann S, William C, Saqran L, Cagsal-Getkin O, Pitstick R, Beier DR, Carlson GA, Spires-Jones TL, Hyman BT
Acta Neuropathologica Communications 2015, 3:14 (24 March 2015)
Abstract http://www.actaneurocomms.org/content/3/1/14/abstract
Full text http://www.actaneurocomms.org/content/3/1/14
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0199-x.pdf

Research
Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury
Ulusoy A, Musgrove RE, Rusconi R, Klinkenberg M, Helwig M, Schneider A, Di Monte DA
Acta Neuropathologica Communications 2015, 3:13 (24 March 2015)
Abstract http://www.actaneurocomms.org/content/3/1/13/abstract
Full text http://www.actaneurocomms.org/content/3/1/13
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0198-y.pdf

Research
Structural alterations of the intestinal epithelial barrier in Parkinson’s disease
Clairembault T, Leclair-Visonneau L, Coron E, Bourreille A, Le Dily S, Vavasseur F, Heymann M, Neunlist M, Derkinderen P
Acta Neuropathologica Communications 2015, 3:12 (10 March 2015)
Abstract http://www.actaneurocomms.org/content/3/1/12/abstract
Full text http://www.actaneurocomms.org/content/3/1/12
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0196-0.pdf
PubMed http://www.actaneurocomms.org/pubmed/25775153

Research
NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma
Georgescu M, Yell P, Mobley BC, Shang P, Georgescu T, Wang SJ, Canoll P, Hatanpaa KJ, White III CL, Raisanen JM
Acta Neuropathologica Communications 2015, 3:11 (8 March 2015)
Abstract http://www.actaneurocomms.org/content/3/1/11/abstract
Full text http://www.actaneurocomms.org/content/3/1/11
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0197-z.pdf
PubMed http://www.actaneurocomms.org/pubmed/25775275

Research
Early neurone loss in Alzheimer’s disease: cortical or subcortical?
Arendt T, Brückner MK, Morawski M, Jäger C, Gertz H
Acta Neuropathologica Communications 2015, 3:10 (10 February 2015)
Abstract http://www.actaneurocomms.org/content/3/1/10/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0187-1.pdf

Research
Loss of angiotensin II receptor expression in dopamine neurons in Parkinson’s disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation
Zawada W, Mrak RE, Biedermann J, Palmer QD, Gentleman SM, Aboud O, Griffin W
Acta Neuropathologica Communications 2015, 3:9 (3 February 2015)
Abstract http://www.actaneurocomms.org/content/3/1/9/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0189-z.pdf
PubMed http://www.actaneurocomms.org/pubmed/25645462

Research
Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severity
Stewart T, Sossi V, Aasly JO, Wszolek ZK, Uitti RJ, Hasegawa K, Yokoyama T, Zabetian CP, Leverenz JB, Stoessl A, Wang Y, Ginghina C, Liu C, Cain KC, Auinger P, Kang U, Jensen P, Shi M, Zhang J
Acta Neuropathologica Communications 2015, 3:7 (31 January 2015)
Abstract http://www.actaneurocomms.org/content/3/1/7/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0185-3.pdf
PubMed http://www.actaneurocomms.org/pubmed/25637461

Research
LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease
Rothaug M, Stroobants S, Schweizer M, Peters J, Zunke F, Allerding M, D’Hooge R, Saftig P, Blanz J
Acta Neuropathologica Communications 2015, 3:6 (31 January 2015)
Abstract http://www.actaneurocomms.org/content/3/1/6/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/s40478-014-0182-y.pdf
PubMed http://www.actaneurocomms.org/pubmed/25637286

Research
Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients
Paré B, Touzel-Deschênes L, Lamontagne R, Lamarre M, Scott F, Khuong HT, Dion PA, Bouchard J, Gould P, Rouleau GA, Dupré N, Berthod F, Gros-Louis F
Acta Neuropathologica Communications 2015, 3:5 (31 January 2015)
Abstract http://www.actaneurocomms.org/content/3/1/5/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/s40478-014-0181-z.pdf
PubMed http://www.actaneurocomms.org/pubmed/25637145

Research
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
Blair LJ, Frauen HD, Zhang B, Nordhues BA, Bijan S, Lin Y, Zamudio F, Hernandez LD, Sabbagh JJ, Selenica MB, Dickey CA
Acta Neuropathologica Communications 2015, 3:8 (31 January 2015)
Abstract http://www.actaneurocomms.org/content/3/1/8/abstract
Full text http://www.actaneurocomms.org/content/3/1/8
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0186-2.pdf
PubMed http://www.actaneurocomms.org/pubmed/25775028

Research
Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma
Pellegatta S, Valletta L, Corbetta C, Patanè M, Zucca I, Riccardi Sirtori F, Bruzzone M, Fogliatto G, Isacchi A, Pollo B, Finocchiaro G
Acta Neuropathologica Communications 2015, 3:4 (21 January 2015)
Abstract http://www.actaneurocomms.org/content/3/1/4/abstract
Full text http://www.actaneurocomms.org/content/3/1/4
PDF http://www.actaneurocomms.org/content/pdf/s40478-014-0180-0.pdf

Research
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid
Nicolini C, Ahn Y, Michalski B, Rho JM, Fahnestock M
Acta Neuropathologica Communications 2015, 3:3 (20 January 2015)
Abstract http://www.actaneurocomms.org/content/3/1/3/abstract
Full text http://www.actaneurocomms.org/content/3/1/3
PDF http://www.actaneurocomms.org/content/pdf/s40478-015-0184-4.pdf
PubMed http://www.actaneurocomms.org/pubmed/25627160








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