Highlights from Breast Cancer Research

Breast Cancer Research Impact Factor: 5.211   Breast Cancer Research Impact Factor: 5.211     Submit Manuscript  |  Editorial Board  |  Submission Guidelines  |  Article Alerts   Dear Dr Wirawan, We would like to share with you some highlights in Breast Cancer Research from November and December 2016. For the full list of articles published in Breast Cancer Research, please visit the journal website. Featured articles Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women Rebbeck et al. report evidence that the BRCA1 mutation in transheterozygotes (TH) may drive these clinical TH phenotypes based on elevated ovarian cancer risk in TH vs. SH2 but not SH1, and earlier age of breast cancer diagnosis in TH vs. SH2 but not SH1. Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods Lloyd-Lewis and colleagues assess the utility of whole-organ tissue clearing protocols in the mouse mammary gland and conclude that most methods were affordable, compatible with standard confocal microscopy and enable high-resolution, 3D imaging and phenotyping of mammary cells and tumours in situ. Safety and efficacy of vinorelbine in combination with pertuzumab and trastuzumab for first-line treatment of patients with HER2-positive locally advanced or metastatic breast cancer: VELVET Cohort 1 final results Perez et al. report the results of this Phase II study, which finds that vinorelbine in combination with pertuzumab and trastuzumab is reasonably well tolerated and offers an alternative for patients who cannot receive docetaxel. Social media Don't forget Breast Cancer Research has its own Twitter account! To stay updated with the latest journal news, please follow @BCRJournal, and make sure to recommend to your colleagues. Review Article Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers In this review, Selli and colleagues summarise current and future biomarkers and signatures for predicting response to endocrine treatment, and discuss the potential for using approved drugs and novel agents to improve outcomes. Submit your research Breast Cancer Research offers fast and thorough peer review, with rapid publication and PubMed indexing after acceptance. All research is open access, giving high visibility to your work. Why not consider publishing your next research article with Breast Cancer Research? To find out whether your article is suitable for the journal, send a presubmission enquiry to editorial@breast-cancer-research.com. Submit Manuscript Editorial Board Submission Guidelines Article Alerts Follow BioMed Central: How to ensure BioMed Central's emails reach your inbox You have received this message in a belief that it would be of interest. If you would not like to receive any further messages from BioMed Central, please visit our general unsubscribe page. For further information or enquiries please contact Customer Services at:info@biomedcentral.com. BioMed Central Ltd 236 Gray's Inn Road, London, WC1X 8HB, United Kingdom. Part of Springer Nature. Privacy Policy BMC40573   www.springernature.com

New in BMC Medicine – December 2016

BMC Medicine Impact Factor: 8.005   BMC Medicine Impact Factor: 8.005     Submit Manuscript  |  Editorial Board  |  Submission Guidelines  |  Article Alerts   Dear Dr Wirawan, We are pleased to share with you our December content update, featuring journal news, top articles and our most recent table of contents. Featured Article Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality A systematic review and meta-analysis reveal that increasing nut consumption by a handful (28 grams) is associated with lower risk of cardiovascular disease and cancer. Significant reductions were seen also for all-cause mortality and mortality from cancer, respiratory disease, diabetes, and infections. From the BMC Medicine blog Tropical medicine, Zika virus disease, and refugee health: BMC Medicine attends ASTMH 2016 BMC Medicine recently attended the American Society for Tropical Medicine and Hygiene (ASTMH) 2016 meeting in Atlanta. Here we present some of the highlights of the conference, including exciting new developments and important challenges in the field of tropical medicine. Magnesium deficiency and its multiple health outcomes Published today in BMC Medicine, a new meta-analysis examines the evidence on the association between magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality. Using data from more than a million people across nine countries it is the largest study of its kind to date. Here lead author Dr. Fudi Wang tells us more. Supporting better decision making for acute infection management in secondary care In a recent study published in BMC Medicine, we set out to explore the way that decisions are made surrounding infection management. We report a study to map the decision making process of medical physicians in secondary care for acute infection management and investigate factors which may hinder or facilitate the effective use of antibiotics. Table of Contents Commentary Taking advantage of unexpected WebCONSORT results Erik Cobo and José Antonio González BMC Medicine 2016 14:204 Tumour response in metastatic renal cell carcinoma treated with tyrosine kinase inhibitors – assessment of intra-tumour heterogeneity Viktoria Stühler and Jens Bedke BMC Medicine 2016 14:201 Opinion Achieving development goals for HIV, tuberculosis and malaria in sub-Saharan Africa through integrated antenatal care: barriers and challenges Freya J. I. Fowkes, Bridget L. Draper, Margaret Hellard and Mark Stoové BMC Medicine 2016 14:202 Modernising epidemic science: enabling patient-centred research during epidemics Amanda M. Rojek and Peter W. Horby BMC Medicine 2016 14:212 Research Adult-onset Still's disease: evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers Piero Ruscitti, Paola Cipriani, Francesco Masedu, Daniela Iacono, Francesco Ciccia, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Onorina Berardicurti, Paola Di Benedetto, Marco Valenti, Giovanni Triolo… BMC Medicine 2016 14:194 Outcomes of notifications to health practitioner boards: a retrospective cohort study Matthew J. Spittal, David M. Studdert, Ron Paterson and Marie M. Bismark BMC Medicine 2016 14:198 Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies Dagfinn Aune, NaNa Keum, Edward Giovannucci, Lars T. Fadnes, Paolo Boffetta, Darren C. Greenwood, Serena Tonstad, Lars J. Vatten, Elio Riboli and Teresa Norat BMC Medicine 2016 14:207 Cost-effectiveness of screening for ovarian cancer amongst postmenopausal women: a model-based economic evaluation Ben Kearns, Jim Chilcott, Sophie Whyte, Louise Preston and Susi Sadler BMC Medicine 2016 14:200 Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort studies Xuexian Fang, Kai Wang, Dan Han, Xuyan He, Jiayu Wei, Lu Zhao, Mustapha Umar Imam, Zhiguang Ping, Yusheng Li, Yuming Xu, Junxia Min and Fudi Wang BMC Medicine 2016 14:210 How effective are volunteers at supporting people in their last year of life? A pragmatic randomised wait-list trial in palliative care (ELSA) Catherine Walshe, Steven Dodd, Matt Hill, Nick Ockenden, Sheila Payne, Nancy Preston and Guillermo Perez Algorta BMC Medicine 2016 14:203 Mapping the decision pathways of acute infection management in secondary care among UK medical physicians: a qualitative study Timothy Miles Rawson, Esmita Charani, Luke Stephen Prockter Moore, Bernard Hernandez, Enrique Castro-Sánchez, Pau Herrero, Pantelis Georgiou and Alison Helen Holmes BMC Medicine 2016 14:208 Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence Qin Wang, Peter Würtz, Kirsi Auro, Ville-Petteri Mäkinen, Antti J. Kangas, Pasi Soininen, Mika Tiainen, Tuulia Tynkkynen, Jari Jokelainen, Kristiina Santalahti, Marko Salmi, Stefan Blankenberg, Tanja Zeller, Jorma Viikari… BMC Medicine 2016 14:205 Cognition in chronic kidney disease: a systematic review and meta-analysis Israel Berger, Sunny Wu, Philip Masson, Patrick J. Kelly, Fiona A. Duthie, William Whiteley, Daniel Parker, David Gillespie and Angela C. Webster BMC Medicine 2016 14:206 Cumulative subgroup analysis to reduce waste in clinical research for individualised medicine Fujian Song and Max O. Bachmann BMC Medicine 2016 14:197 What works for whom in pharmacist-led smoking cessation support: realist review Trisha Greenhalgh, Fraser Macfarlane, Liz Steed and Robert Walton BMC Medicine 2016 14:209 Impact of pneumococcal conjugate vaccines on pneumococcal meningitis cases in France between 2001 and 2014: a time series analysis Anna Alari, Hélène Chaussade, Matthieu Domenech De Cellès, Lénaig Le Fouler, Emmanuelle Varon, Lulla Opatowski, Didier Guillemot and Laurence Watier BMC Medicine 2016 14:211 Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis Rita PavasiniEmail author, Jack Guralnik, Justin C. Brown, Mauro di Bari, Matteo Cesari, Francesco Landi, Bert Vaes, Delphine Legrand, Joe Verghese, Cuiling Wang, Sari Stenholm, Luigi Ferrucci, Jennifer C. Lai, Anna Arnau… BMC Medicine 2016 14:215 Comparative safety and effectiveness of serotonin receptor antagonists in patients undergoing chemotherapy: a systematic review and network meta-analysis Andrea C. Tricco, Erik Blondal, Areti Angeliki Veroniki, Charlene Soobiah, Afshin Vafaei, John Ivory, Lisa Strifler, Roberta Cardoso, Emily Reynen, Vera Nincic, Huda Ashoor, Joanne Ho, Carmen Ng, Christy Johnson, Erin Lillie… BMC Medicine 2016 14:216 Benefits of publishing with us • 2015 median turnover times: initial decision three days; first decision after peer review 40 days • Portable peer review • Broad medical readership Follow @BMCMedicine on Twitter Submit Manuscript Editorial Board Submission Guidelines Article Alerts Follow BioMed Central: How to ensure BioMed Central's emails reach your inbox You have received this message in a belief that it would be of interest. If you would not like to receive any further messages from BioMed Central, please visit our general unsubscribe page. For further information or enquiries please contact Customer Services at:info@biomedcentral.com. BioMed Central Ltd 236 Gray's Inn Road, London, WC1X 8HB, United Kingdom. Part of Springer Nature. Privacy Policy BMC40566   www.springernature.com

Latest Article Alert from Journal of Occupational Medicine and Toxicology

The following new articles have just been published in Journal of Occupational Medicine and Toxicology




Research
Work-related exposures and disorders among physical therapists: experiences and beliefs of professional representatives assessed using a qualitative approach
Girbig M, Freiberg A, Deckert S, Druschke D, Kopkow C, Nienhaus A, Seidler A
Journal of Occupational Medicine and Toxicology 2017, 12:2 (7 January 2017)
Abstract http://occup-med.biomedcentral.com/articles/10.1186/s12995-016-0147-0#Abs1
Full text http://occup-med.biomedcentral.com/articles/10.1186/s12995-016-0147-0
PDF http://occup-med.biomedcentral.com/track/pdf/10.1186/s12995-016-0147-0
Research
QFT-Plus: a plus in variability? – Evaluation of new generation IGRA in serial testing of students with a migration background in Germany
Knierer J, Gallegos Morales E, Schablon A, Nienhaus A, Kersten J
Journal of Occupational Medicine and Toxicology 2017, 12:1 (5 January 2017)
Abstract http://occup-med.biomedcentral.com/articles/10.1186/s12995-016-0148-z#Abs1
Full text http://occup-med.biomedcentral.com/articles/10.1186/s12995-016-0148-z
PDF http://occup-med.biomedcentral.com/track/pdf/10.1186/s12995-016-0148-z







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