Late-life depression is commonly associated with cognitive impairment. In a community-based cohort study of 7381 elderly participants, the effects of antidepressant treatment on cognitive performance were studied over a 10-year period. Five cognitive domains were assessed during follow-up, and no significant differences were observed between antidepressant users and non-users. The results of this study indicate that there is no evidence for an association between antidepressant use and post-treatment cognitive decline in elderly people.
Cees van Nieuwkoop, Willize E. van der Starre, Janneke E. Stalenhoef, Anna M. van Aartrijk, Tanny J. K. van der Reijden, Albert M. Vollaard, Nathalie M. Delfos, Jan W. van 't Wout, Jeanet W. Blom, Ida C. Spelt… BMC Medicine 2017 15:70
Marion Savina, Axel Le Cesne, Jean-Yves Blay, Isabelle Ray-Coquard, Olivier Mir, Maud Toulmonde, Sophie Cousin, Philippe Terrier, Dominique Ranchere-Vince, Pierre Meeus, Eberhard Stoeckle, Charles Honoré… BMC Medicine 2017 15:78
Sara Charmsaz, Éamon Hughes, Fiona T. Bane, Paul Tibbitts, Marie McIlroy, Christopher Byrne, Sinéad Cocchiglia, Jean McBryan, Bryan T. Hennessy, Róisín M. Dwyer, Michael J. Kerin, Arnold D. Hill and Leonie S. Young BMC Medicine 2017 15:79
Renato Quispe, Aditya Hendrani, Mohamed B. Elshazly, Erin D. Michos, John W. McEvoy, Michael J. Blaha, Maciej Banach, Krishnaji R. Kulkarni, Peter P. Toth, Josef Coresh, Roger S. Blumenthal… BMC Medicine 2017 15:83
Rajashree Mishra, Alessandra Chesi, Diana L. Cousminer, Mohammad I. Hawa, Jonathan P. Bradfield, Kenyaita M. Hodge, Vanessa C. Guy, Hakon Hakonarson, Didac Mauricio, Nanette C. Schloot, Knud B. Yderstræde… BMC Medicine 2017 15:88
Tjibbe Donker, Katherine L. Henderson, Katie L. Hopkins, Andrew R. Dodgson, Stephanie Thomas, Derrick W. Crook, Tim E. A. Peto, Alan P. Johnson, Neil Woodford, A. Sarah Walker and Julie V. Robotham BMC Medicine 2017 15:86
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