| Dear Dr Wirawan,
We are pleased to share with you our April content update, featuring journal news, top articles and our most recent table of contents. Featured Article Late-life depression is commonly associated with cognitive impairment. In a community-based cohort study of 7381 elderly participants, the effects of antidepressant treatment on cognitive performance were studied over a 10-year period. Five cognitive domains were assessed during follow-up, and no significant differences were observed between antidepressant users and non-users. The results of this study indicate that there is no evidence for an association between antidepressant use and post-treatment cognitive decline in elderly people. Table of Contents Commentary Opinion Research Treatment duration of febrile urinary tract infection: a pragmatic randomized, double-blind, placebo-controlled non-inferiority trial in men and women | Cees van Nieuwkoop, Willize E. van der Starre, Janneke E. Stalenhoef, Anna M. van Aartrijk, Tanny J. K. van der Reijden, Albert M. Vollaard, Nathalie M. Delfos, Jan W. van 't Wout, Jeanet W. Blom, Ida C. Spelt… BMC Medicine 2017 15:70 | Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study | Veronika Fedirko, Hao Quang Tran, Andrew T. Gewirtz, Magdalena Stepien, Antonia Trichopoulou, Krasimira Aleksandrova, Anja Olsen, Anne Tjønneland, Kim Overvad, Franck Carbonnel, Marie-Christine Boutron-Ruault… BMC Medicine 2017 15:72 | Patterns of care and outcomes of patients with METAstatic soft tissue SARComa in a real-life setting: the METASARC observational study | Marion Savina, Axel Le Cesne, Jean-Yves Blay, Isabelle Ray-Coquard, Olivier Mir, Maud Toulmonde, Sophie Cousin, Philippe Terrier, Dominique Ranchere-Vince, Pierre Meeus, Eberhard Stoeckle, Charles Honoré… BMC Medicine 2017 15:78 | S100β as a serum marker in endocrine resistant breast cancer | Sara Charmsaz, Éamon Hughes, Fiona T. Bane, Paul Tibbitts, Marie McIlroy, Christopher Byrne, Sinéad Cocchiglia, Jean McBryan, Bryan T. Hennessy, Róisín M. Dwyer, Michael J. Kerin, Arnold D. Hill and Leonie S. Young BMC Medicine 2017 15:79 | Accuracy of low-density lipoprotein cholesterol estimation at very low levels | Renato Quispe, Aditya Hendrani, Mohamed B. Elshazly, Erin D. Michos, John W. McEvoy, Michael J. Blaha, Maciej Banach, Krishnaji R. Kulkarni, Peter P. Toth, Josef Coresh, Roger S. Blumenthal… BMC Medicine 2017 15:83 | Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes | Rajashree Mishra, Alessandra Chesi, Diana L. Cousminer, Mohammad I. Hawa, Jonathan P. Bradfield, Kenyaita M. Hodge, Vanessa C. Guy, Hakon Hakonarson, Didac Mauricio, Nanette C. Schloot, Knud B. Yderstræde… BMC Medicine 2017 15:88 | Review Benefits of publishing with us • | 2016 median turnover times: initial decision three days; first decision after peer review 40 days | • | Portable peer review | • | Broad medical readership | Follow @BMCMedicine on Twitter Kind regards, The BMC Medicine team *The Impact Factor (IF) is just one measure used for evaluating the impact of research. For further information on the IF and alternative metrics used to measure the impact of research, please click here. | | | |