May 4, 2014

Latest Article Alert from Acta Neuropathologica Communications

The following new articles have just been published in Acta Neuropathologica Communications

For articles using Author Version-first publication you will see a provisional PDF corresponding to the accepted manuscript. In these instances, the fully formatted Final Version PDF and full text (HTML) versions will follow in due course.

Case report
Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor
Küsters-Vandevelde HV, Willemsen AE, Groenen PJ, Küsters B, Lammens M, Wesseling P, Djafarihamedani M, Rijntjes J, Delye H, Willemsen MA, van Herpen CM, Blokx WA
Acta Neuropathologica Communications 2014, 2:41 (8 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/41/abstract
Full text http://www.actaneurocomms.org/content/2/1/41
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-41.pdf
PubMed http://www.actaneurocomms.org/pubmed/24713450

Case report
Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer
Ling H, Kara E, Revesz T, Lees AJ, Plant GT, Martino D, Houlden H, Hardy J, Holton JL
Acta Neuropathologica Communications 2014, 2:24 (21 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/24/abstract
Full text http://www.actaneurocomms.org/content/2/1/24
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-24.pdf
PubMed http://www.actaneurocomms.org/pubmed/24559032

Case report
Two cases of multinodular and vacuolating neuronal tumour
Bodi I, Curran O, Selway R, Elwes R, Burrone J, Laxton R, Al-Sarraj S, Honavar M
Acta Neuropathologica Communications 2014, 2:7 (20 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/7/abstract
Full text http://www.actaneurocomms.org/content/2/1/7
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-7.pdf
PubMed http://www.actaneurocomms.org/pubmed/24444358

Case report
Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases
Kim M, Cali I, Oehler A, Fong JC, Wong K, See T, Katz JS, Gambetti P, Bettcher BM, DeArmond SJ, Geschwind MD
Acta Neuropathologica Communications 2013, 1:80 (12 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/80/abstract
Full text http://www.actaneurocomms.org/content/1/1/80
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-80.pdf
PubMed http://www.actaneurocomms.org/pubmed/24330864

Letter to the Editor
Metabolic alterations due to IDH1 mutation in glioma: opening for therapeutic opportunities?
N Mustafa DA, Swagemakers SM, Buise L, van der Spek PJ, Kros JM
Acta Neuropathologica Communications 2014, 2:6 (9 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/6/abstract
Full text http://www.actaneurocomms.org/content/2/1/6
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-6.pdf
PubMed http://www.actaneurocomms.org/pubmed/24405933

Methodology article
Optimization of electron microscopy for human brains with long-term fixation and fixed-frozen sections
Liu X, Schumann CM
Acta Neuropathologica Communications 2014, 2:42 (11 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/42/abstract
Full text http://www.actaneurocomms.org/content/2/1/42
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-42.pdf
PubMed http://www.actaneurocomms.org/pubmed/24721148

Methodology article
Generation of iPSC lines from archived non-cryoprotected biobanked dura mater
Sproul AA, Vensand LB, Dusenberry CR, Jacob S, Vonsattel JG, Paull DJ, Shelanski ML, Crary JF, Noggle SA
Acta Neuropathologica Communications 2014, 2:4 (7 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/4/abstract
Full text http://www.actaneurocomms.org/content/2/1/4
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-4.pdf
PubMed http://www.actaneurocomms.org/pubmed/24398250

Research
Early white matter changes in CADASIL: evidence of segmental intramyelinic oedema in a pre-clinical mouse model
Cognat E, Cleophax S, Domenga-Denier V, Joutel A
Acta Neuropathologica Communications 2014, 2:49 (30 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/49/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-49.pdf

Research
Neuromyelitis optica pathology in rats following intraperitoneal injection of NMO-IgG and intracerebral needle injury
Asavapanumas N, Verkman AS
Acta Neuropathologica Communications 2014, 2:48 (24 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/48/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-48.pdf
PubMed http://www.actaneurocomms.org/pubmed/24758159

Research
The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test
Boizot A, Talmat-Amar Y, Morrogh D, Kuntz NL, Halbert C, Chabrol B, Houlden H, Stojkovic T, Schulman BA, Rautenstrauss B, Bomont P
Acta Neuropathologica Communications 2014, 2:47 (24 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/47/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-47.pdf
PubMed http://www.actaneurocomms.org/pubmed/24758703

Research
Diagnostic effectiveness of quantitative [18F]flutemetamol PET imaging for detection of fibrillar amyloid β using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus
Leinonen V, Rinne JO, Wong DF, Wolk DA, Trojanowski JQ, Sherwin PF, Smith A, Heurling K, Su M, Grachev ID
Acta Neuropathologica Communications 2014, 2:46 (22 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/46/abstract
Full text http://www.actaneurocomms.org/content/2/1/46
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-46.pdf
PubMed http://www.actaneurocomms.org/pubmed/24755237

Research
Layer-specific gene expression in epileptogenic type II focal cortical dysplasia: normal-looking neurons reveal the presence of a hidden laminar organization
Rossini L, Medici V, Tassi L, Cardinale F, Tringali G, Bramerio M, Villani F, Spreafico R, Garbelli R
Acta Neuropathologica Communications 2014, 2:45 (15 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/45/abstract
Full text http://www.actaneurocomms.org/content/2/1/45
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-45.pdf
PubMed http://www.actaneurocomms.org/pubmed/24735483

Research
Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype
Malfatti E, Lehtokari V, Böhm J, De Winter JM, Schäffer U, Estournet B, Quijano-Roy S, Monges S, Lubieniecki F, Bellance R, Viou MT, Madelaine A, Wu B, Taratuto AL, Eymard B, Pelin K, Fardeau M, Ottenheijm CA, Wallgren-Pettersson C, Laporte J, Romero NB
Acta Neuropathologica Communications 2014, 2:44 (12 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/44/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-44.pdf
PubMed http://www.actaneurocomms.org/pubmed/24725366

Research
Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies
Wacker J, Rönicke R, Westermann M, Wulff M, Reymann KG, Dobson CM, Horn U, Crowther DC, Luheshi LM, Fändrich M
Acta Neuropathologica Communications 2014, 2:43 (11 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/43/abstract
Full text http://www.actaneurocomms.org/content/2/1/43
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-43.pdf
PubMed http://www.actaneurocomms.org/pubmed/24725347

Research
Tau accumulation in the nucleus accumbens in tangle-predominant dementia
Kawakami I, Hasegawa M, Arai T, Ikeda K, Oshima K, Niizato K, Aoki N, Omi K, Higashi S, Hosokawa M, Hirayasu Y, Akiyama H
Acta Neuropathologica Communications 2014, 2:40 (8 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/40/abstract
Full text http://www.actaneurocomms.org/content/2/1/40
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-40.pdf
PubMed http://www.actaneurocomms.org/pubmed/24708916

Research
NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma
Fiaschetti G, Schroeder C, Castelletti D, Arcaro A, Westermann F, Baumgartner M, Shalaby T, Grotzer MA
Acta Neuropathologica Communications 2014, 2:39 (7 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/39/abstract
Full text http://www.actaneurocomms.org/content/2/1/39
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-39.pdf
PubMed http://www.actaneurocomms.org/pubmed/24708907

Research
Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons
van Dis V, Kuijpers M, Haasdijk ED, Teuling E, Oakes SA, Hoogenraad CC, Jaarsma D
Acta Neuropathologica Communications 2014, 2:38 (7 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/38/abstract
Full text http://www.actaneurocomms.org/content/2/1/38
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-38.pdf
PubMed http://www.actaneurocomms.org/pubmed/24708899

Research
Interaction of transactive response DNA binding protein 43 with nuclear factor kappaB in mild cognitive impairment with episodic memory deficits
Ohta Y, Tremblay C, Schneider JA, Bennett DA, Calon F, Julien J
Acta Neuropathologica Communications 2014, 2:37 (1 April 2014)
Abstract http://www.actaneurocomms.org/content/2/1/37/abstract
Provisional PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-37.pdf
PubMed http://www.actaneurocomms.org/pubmed/24690380

Research
Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression
Weyer SW, Zagrebelsky M, Herrmann U, Hick M, Ganss L, Gobbert J, Gruber M, Altmann C, Korte M, Deller T, Müller UC
Acta Neuropathologica Communications 2014, 2:36 (31 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/36/abstract
Full text http://www.actaneurocomms.org/content/2/1/36
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-36.pdf
PubMed http://www.actaneurocomms.org/pubmed/24684730

Research
Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain
Saadoun S, Waters P, Owens GP, Bennett JL, Vincent A, Papadopoulos MC
Acta Neuropathologica Communications 2014, 2:35 (31 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/35/abstract
Full text http://www.actaneurocomms.org/content/2/1/35
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-35.pdf
PubMed http://www.actaneurocomms.org/pubmed/24685353

Research
Critical role of TNF-alpha-TNFR1 signaling in intracranial aneurysm formation
Aoki T, Fukuda M, Nishimura M, Nozaki K, Narumiya S
Acta Neuropathologica Communications 2014, 2:34 (31 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/34/abstract
Full text http://www.actaneurocomms.org/content/2/1/34
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-34.pdf
PubMed http://www.actaneurocomms.org/pubmed/24685329

Research
Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins
Kwong LK, Irwin DJ, Walker AK, Xu Y, Riddle DM, Trojanowski JQ, Lee VY
Acta Neuropathologica Communications 2014, 2:33 (31 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/33/abstract
Full text http://www.actaneurocomms.org/content/2/1/33
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-33.pdf
PubMed http://www.actaneurocomms.org/pubmed/24690345

Research
Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
Ding D, Lim K, Eberhart CG
Acta Neuropathologica Communications 2014, 2:31 (31 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/31/abstract
Full text http://www.actaneurocomms.org/content/2/1/31
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-31.pdf
PubMed http://www.actaneurocomms.org/pubmed/24685274

Research
In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques
Burgold S, Filser S, Dorostkar MM, Schmidt B, Herms J
Acta Neuropathologica Communications 2014, 2:30 (28 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/30/abstract
Full text http://www.actaneurocomms.org/content/2/1/30
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-30.pdf
PubMed http://www.actaneurocomms.org/pubmed/24678659

Research
Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA
Bétemps D, Verchère J, Brot S, Morignat E, Bousset L, Gaillard D, Lakhdar L, Melki R, Baron T
Acta Neuropathologica Communications 2014, 2:29 (13 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/29/abstract
Full text http://www.actaneurocomms.org/content/2/1/29
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-29.pdf
PubMed http://www.actaneurocomms.org/pubmed/24624994

Research
Brain-region–specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism
Wegiel J, Flory M, Kuchna I, Nowicki K, Ma S, Imaki H, Wegiel J, Cohen IL, London E, Brown W, Wisniewski T
Acta Neuropathologica Communications 2014, 2:28 (10 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/28/abstract
Full text http://www.actaneurocomms.org/content/2/1/28
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-28.pdf
PubMed http://www.actaneurocomms.org/pubmed/24612906

Research
α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets
Rothhammer V, Muschaweckh A, Gasteiger G, Petermann F, Heink S, Busch DH, Heikenwälder M, Hemmer B, Drexler I, Korn T
Acta Neuropathologica Communications 2014, 2:27 (7 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/27/abstract
Full text http://www.actaneurocomms.org/content/2/1/27
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-27.pdf
PubMed http://www.actaneurocomms.org/pubmed/24606807

Research
Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition
Toledo JB, Weiner MW, Wolk DA, Da X, Chen K, Arnold SE, Jagust W, Jack C, Reiman EM, Davatzikos C, Shaw LM, Trojanowski JQ, for the Alzheimer?s Disease Neuroimaging Initiative
Acta Neuropathologica Communications 2014, 2:26 (6 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/26/abstract
Full text http://www.actaneurocomms.org/content/2/1/26
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-26.pdf
PubMed http://www.actaneurocomms.org/pubmed/24602322

Research
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan J, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, Donnelly PS, Crouch PJ, Tammen I, White AR, Kanninen KM
Acta Neuropathologica Communications 2014, 2:25 (28 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/25/abstract
Full text http://www.actaneurocomms.org/content/2/1/25
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-25.pdf
PubMed http://www.actaneurocomms.org/pubmed/24581221

Research
The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma
Carvalho D, Mackay A, Bjerke L, Grundy RG, Lopes C, Reis RM, Jones C
Acta Neuropathologica Communications 2014, 2:23 (18 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/23/abstract
Full text http://www.actaneurocomms.org/content/2/1/23
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-23.pdf
PubMed http://www.actaneurocomms.org/pubmed/24548782

Research
MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies
Lund H, Gustafsson E, Svensson A, Nilsson M, Berg M, Sunnemark D, von Euler G
Acta Neuropathologica Communications 2014, 2:22 (17 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/22/abstract
Full text http://www.actaneurocomms.org/content/2/1/22
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-22.pdf
PubMed http://www.actaneurocomms.org/pubmed/24533944

Research
Phenotypic profile of alternative activation marker CD163 is different in Alzheimer’s and Parkinson’s disease
Pey P, Pearce RK, Kalaitzakis ME, Griffin WT, Gentleman SM
Acta Neuropathologica Communications 2014, 2:21 (14 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/21/abstract
Full text http://www.actaneurocomms.org/content/2/1/21
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-21.pdf
PubMed http://www.actaneurocomms.org/pubmed/24528486

Research
Autophagy-lysosome pathway associated neuropathology and axonal degeneration in the brains of alpha-galactosidase A-deficient mice
Nelson MP, Tse TE, O’Quinn DB, Percival SM, Jaimes EA, Warnock DG, Shacka JJ
Acta Neuropathologica Communications 2014, 2:20 (14 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/20/abstract
Full text http://www.actaneurocomms.org/content/2/1/20
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-20.pdf
PubMed http://www.actaneurocomms.org/pubmed/24529306

Research
D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma
Pusch S, Schweizer L, Beck A, Lehmler J, Weissert S, Balss J, Miller AK, von Deimling A
Acta Neuropathologica Communications 2014, 2:19 (14 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/19/abstract
Full text http://www.actaneurocomms.org/content/2/1/19
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-19.pdf
PubMed http://www.actaneurocomms.org/pubmed/24529257

Research
Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups
Gupta K, Orisme W, Harreld JH, Qaddoumi I, Dalton JD, Punchihewa C, Collins-Underwood R, Robertson T, Tatevossian RG, Ellison DW
Acta Neuropathologica Communications 2014, 2:18 (14 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/18/abstract
Full text http://www.actaneurocomms.org/content/2/1/18
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-18.pdf
PubMed http://www.actaneurocomms.org/pubmed/24529209

Research
Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease
George S, Rönnbäck A, Gouras GK, Petit GH, Grueninger F, Winblad B, Graff C, Brundin P
Acta Neuropathologica Communications 2014, 2:17 (11 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/17/abstract
Full text http://www.actaneurocomms.org/content/2/1/17
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-17.pdf
PubMed http://www.actaneurocomms.org/pubmed/24517102

Research
Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury
Sokolowski JD, Gamage KK, Heffron DS, LeBlanc AC, Deppmann CD, Mandell JW
Acta Neuropathologica Communications 2014, 2:16 (7 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/16/abstract
Full text http://www.actaneurocomms.org/content/2/1/16
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-16.pdf
PubMed http://www.actaneurocomms.org/pubmed/24507707

Research
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
Dujardin S, Lécolle K, Caillierez R, Bégard S, Zommer N, Lachaud C, Carrier S, Dufour N, Aurégan G, Winderickx J, Hantraye P, Déglon N, Colin M, Buée L
Acta Neuropathologica Communications 2014, 2:14 (30 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/14/abstract
Full text http://www.actaneurocomms.org/content/2/1/14
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-14.pdf
PubMed http://www.actaneurocomms.org/pubmed/24479894

Research
Mechanism of metabolic stroke and spontaneous cerebral hemorrhage in glutaric aciduria type I
Zinnanti WJ, Lazovic J, Housman C, Antonetti DA, Koeller DM, Connor JR, Steinman L
Acta Neuropathologica Communications 2014, 2:13 (27 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/13/abstract
Full text http://www.actaneurocomms.org/content/2/1/13
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-13.pdf
PubMed http://www.actaneurocomms.org/pubmed/24468193

Research
Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease
Ceccom J, Loukh N, Lauwers-Cances V, Touriol C, Nicaise Y, Gentil C, Uro-Coste E, Pitson S, Maurage C, Duyckaerts C, Cuvillier O, Delisle M
Acta Neuropathologica Communications 2014, 2:12 (27 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/12/abstract
Full text http://www.actaneurocomms.org/content/2/1/12
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-12.pdf
PubMed http://www.actaneurocomms.org/pubmed/24468113

Research
Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis-comparison between Onuf’s neurons and other sacral motor neurons-
Takeda T, Uchihara T, Nakayama Y, Nakamura A, Sasaki S, Kakei S, Uchiyama S, Duyckaerts C, Yoshida M
Acta Neuropathologica Communications 2014, 2:11 (27 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/11/abstract
Full text http://www.actaneurocomms.org/content/2/1/11
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-11.pdf
PubMed http://www.actaneurocomms.org/pubmed/24468079

Research
Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion
Merve A, Dubuc AM, Zhang X, Remke M, Baxter PA, Li X, Taylor MD, Marino S
Acta Neuropathologica Communications 2014, 2:10 (24 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/10/abstract
Full text http://www.actaneurocomms.org/content/2/1/10
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-10.pdf
PubMed http://www.actaneurocomms.org/pubmed/24460684

Research
Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis
Couttas TA, Kain N, Daniels B, Lim X, Shepherd C, Kril J, Pickford R, Li H, Garner B, Don AS
Acta Neuropathologica Communications 2014, 2:9 (23 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/9/abstract
Full text http://www.actaneurocomms.org/content/2/1/9
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-9.pdf
PubMed http://www.actaneurocomms.org/pubmed/24456642

Research
Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein
Rangel A, Race B, Phillips K, Striebel J, Kurtz N, Chesebro B
Acta Neuropathologica Communications 2014, 2:8 (21 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/8/abstract
Full text http://www.actaneurocomms.org/content/2/1/8
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-8.pdf
PubMed http://www.actaneurocomms.org/pubmed/24447368

Research
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome
Yang M, Rainone A, Shi X, Fournier S, Zhang J
Acta Neuropathologica Communications 2014, 2:5 (8 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/5/abstract
Full text http://www.actaneurocomms.org/content/2/1/5
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-5.pdf
PubMed http://www.actaneurocomms.org/pubmed/24401681

Research
SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease
Khan RS, Dine K, Das Sarma J, Shindler KS
Acta Neuropathologica Communications 2014, 2:3 (2 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/3/abstract
Full text http://www.actaneurocomms.org/content/2/1/3
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-3.pdf
PubMed http://www.actaneurocomms.org/pubmed/24383546

Research
The value of muscle biopsies in Pompe disease: identifying lipofuscin inclusions in juvenile- and adult-onset patients
Feeney EJ, Austin S, Chien Y, Mandel H, Schoser B, Prater S, Hwu W, Ralston E, Kishnani PS, Raben N
Acta Neuropathologica Communications 2014, 2:2 (2 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/2/abstract
Full text http://www.actaneurocomms.org/content/2/1/2
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-2.pdf
PubMed http://www.actaneurocomms.org/pubmed/24383498

Research
The identification of mitochondrial DNA variants in glioblastoma multiforme
Yeung K, Dickinson A, Donoghue JF, Polekhina G, White SJ, Grammatopoulos DK, McKenzie M, Johns TG, John J
Acta Neuropathologica Communications 2014, 2:1 (2 January 2014)
Abstract http://www.actaneurocomms.org/content/2/1/1/abstract
Full text http://www.actaneurocomms.org/content/2/1/1
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-1.pdf
PubMed http://www.actaneurocomms.org/pubmed/24383468

Research
T cell-activation in neuromyelitis optica lesions plays a role in their formation
Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer M, Machado-Santos J, Mader S, Ellwart JW, Misu T, Fujihara K, Wekerle H, Reindl M, Lassmann H, Bradl M
Acta Neuropathologica Communications 2013, 1:85 (24 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/85/abstract
Full text http://www.actaneurocomms.org/content/1/1/85
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-85.pdf
PubMed http://www.actaneurocomms.org/pubmed/24367907

Research
Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis
Hampton DW, Serio A, Pryce G, Al-Izki S, Franklin RJ, Giovannoni G, Baker D, Chandran S
Acta Neuropathologica Communications 2013, 1:84 (23 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/84/abstract
Full text http://www.actaneurocomms.org/content/1/1/84
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-84.pdf
PubMed http://www.actaneurocomms.org/pubmed/24364862

Research
A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease
Al-Hilaly YK, Williams TL, Stewart-Parker M, Ford L, Skaria E, Cole M, Bucher W, Morris KL, Sada A, Thorpe JR, Serpell LC
Acta Neuropathologica Communications 2013, 1:83 (18 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/83/abstract
Full text http://www.actaneurocomms.org/content/1/1/83
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-83.pdf
PubMed http://www.actaneurocomms.org/pubmed/24351276

Research
Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice
Hoffmann NA, Dorostkar MM, Blumenstock S, Goedert M, Herms J
Acta Neuropathologica Communications 2013, 1:82 (17 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/82/abstract
Full text http://www.actaneurocomms.org/content/1/1/82
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-82.pdf
PubMed http://www.actaneurocomms.org/pubmed/24344647

Research
Heavy metals in locus ceruleus and motor neurons in motor neuron disease
Pamphlett R, Kum Jew S
Acta Neuropathologica Communications 2013, 1:81 (12 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/81/abstract
Full text http://www.actaneurocomms.org/content/1/1/81
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-81.pdf
PubMed http://www.actaneurocomms.org/pubmed/24330485

Research
Myositis facilitates preclinical accumulation of pathological prion protein in muscle
Neumann M, Krasemann S, Schröck K, Steinbach K, Glatzel M
Acta Neuropathologica Communications 2013, 1:78 (3 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/78/abstract
Full text http://www.actaneurocomms.org/content/1/1/78
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-78.pdf
PubMed http://www.actaneurocomms.org/pubmed/24299111

Research
The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice
Rijal Upadhaya A, Scheibe F, Kosterin I, Abramowski D, Gerth J, Kumar S, Liebau S, Yamaguchi H, Walter J, Staufenbiel M, Thal D
Acta Neuropathologica Communications 2013, 1:77 (18 November 2013)
Abstract http://www.actaneurocomms.org/content/1/1/77/abstract
Full text http://www.actaneurocomms.org/content/1/1/77
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-77.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252227

Research
Brains from non-Alzheimer’s individuals containing amyloid deposits accelerate Aβ deposition in vivo
Duran-Aniotz C, Morales R, Moreno-Gonzalez I, Hu P, Soto C
Acta Neuropathologica Communications 2013, 1:76 (18 November 2013)
Abstract http://www.actaneurocomms.org/content/1/1/76/abstract
Full text http://www.actaneurocomms.org/content/1/1/76
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-76.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252208

Research
Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation
ElAli A, Thériault P, Préfontaine P, Rivest S
Acta Neuropathologica Communications 2013, 1:75 (13 November 2013)
Abstract http://www.actaneurocomms.org/content/1/1/75/abstract
Full text http://www.actaneurocomms.org/content/1/1/75
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-75.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252187

Research
Deciphering the pathogenesis of sporadic Creutzfeldt-Jakob disease with codon 129 M/V and type 2 abnormal prion protein
Kobayashi A, Iwasaki Y, Otsuka H, Yamada M, Yoshida M, Matsuura Y, Mohri S, Kitamoto T
Acta Neuropathologica Communications 2013, 1:74 (13 November 2013)
Abstract http://www.actaneurocomms.org/content/1/1/74/abstract
Full text http://www.actaneurocomms.org/content/1/1/74
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-74.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252157

Research
In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology
Trujillo-Estrada L, Jimenez S, De Castro V, Torres M, Baglietto-Vargas D, Moreno-Gonzalez I, Navarro V, Sanchez-Varo R, Sanchez-Mejias E, Davila J, Vizuete M, Gutierrez A, Vitorica J
Acta Neuropathologica Communications 2013, 1:73 (12 November 2013)
Abstract http://www.actaneurocomms.org/content/1/1/73/abstract
Full text http://www.actaneurocomms.org/content/1/1/73
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-73.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252759

Research
Rapidly progressive dementia with thalamic degeneration and peculiar cortical prion protein immunoreactivity, but absence of proteinase K resistant PrP: a new disease entity?
Kovacs GG, Peden A, Weis S, Höftberger R, Berghoff AS, Yull H, Ströbel T, Koppi S, Katzenschlager R, Langenscheidt D, Assar H, Zaruba E, Gröner A, Voigtländer T, Puska G, Hametner E, Grams A, Muigg A, Knoflach M, László L, Ironside JW, Head MW, Budka H
Acta Neuropathologica Communications 2013, 1:72 (11 November 2013)
Abstract http://www.actaneurocomms.org/content/1/1/72/abstract
Full text http://www.actaneurocomms.org/content/1/1/72
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-72.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252716

Research
Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall
Frösen J, Tulamo R, Heikura T, Sammalkorpi S, Niemelä M, Hernesniemi J, Levonen A, Hörkkö S, Ylä-Herttuala S
Acta Neuropathologica Communications 2013, 1:71 (28 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/71/abstract
Full text http://www.actaneurocomms.org/content/1/1/71
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-71.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252658

Research
Astrocytes differentially respond to inflammatory autoimmune insults and imbalances of neural activity
Jukkola P, Guerrero T, Gray V, Gu C
Acta Neuropathologica Communications 2013, 1:70 (23 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/70/abstract
Full text http://www.actaneurocomms.org/content/1/1/70
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-70.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252623

Research
Cerebellar hemorrhagic injury in premature infants occurs during a vulnerable developmental period and is associated with wider neuropathology
Haines KM, Wang W, Pierson CR
Acta Neuropathologica Communications 2013, 1:69 (21 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/69/abstract
Full text http://www.actaneurocomms.org/content/1/1/69
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-69.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252570

Research
Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72
Mann DM, Rollinson S, Robinson A, Bennion Callister J, Thompson JC, Snowden JS, Gendron T, Petrucelli L, Masuda-Suzukake M, Hasegawa M, Davidson Y, Pickering-Brown S
Acta Neuropathologica Communications 2013, 1:68 (14 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/68/abstract
Full text http://www.actaneurocomms.org/content/1/1/68
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-68.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252525

Research
Focal cortical dysplasias in autism spectrum disorders
Casanova MF, El-Baz AS, Kamat SS, Dombroski BA, Khalifa F, Elnakib A, Soliman A, Allison-McNutt A, Switala AE
Acta Neuropathologica Communications 2013, 1:67 (11 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/67/abstract
Full text http://www.actaneurocomms.org/content/1/1/67
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-67.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252498

Research
G-protein coupled receptor expression patterns delineate medulloblastoma subgroups
Whittier KL, Boese EA, Gibson-Corley KN, Kirby PA, Darbro BW, Qian Q, Ingram WJ, Robertson T, Remke M, Taylor MD, O’Dorisio M
Acta Neuropathologica Communications 2013, 1:66 (10 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/66/abstract
Full text http://www.actaneurocomms.org/content/1/1/66
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-66.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252460

Research
Clinical and multimodal biomarker correlates of ADNI neuropathological findings
Toledo JB, Cairns NJ, Da X, Chen K, Carter D, Fleisher A, Householder E, Ayutyanont N, Roontiva A, Bauer RJ, Eisen P, Shaw LM, Davatzikos C, Weiner MW, Reiman EM, Morris JC, Trojanowski JQ, the Alzheimer?s Disease Neuroimaging Initiative
Acta Neuropathologica Communications 2013, 1:65 (9 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/65/abstract
Full text http://www.actaneurocomms.org/content/1/1/65
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-65.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252435

Research
Nerve hyperplasia: a unique feature of ketamine cystitis
Baker SC, Stahlschmidt J, Oxley J, Hinley J, Eardley I, Marsh F, Gillatt D, Fulford S, Southgate J
Acta Neuropathologica Communications 2013, 1:64 (8 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/64/abstract
Full text http://www.actaneurocomms.org/content/1/1/64
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-64.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252413

Research
Human fetal inner ear involvement in congenital cytomegalovirus infection
Gabrielli L, Bonasoni M, Santini D, Piccirilli G, Chiereghin A, Guerra B, Landini M, Capretti M, Lanari M, Lazzarotto T
Acta Neuropathologica Communications 2013, 1:63 (2 October 2013)
Abstract http://www.actaneurocomms.org/content/1/1/63/abstract
Full text http://www.actaneurocomms.org/content/1/1/63
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-63.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252374

Research
The link between intraneuronal N-truncated amyloid-β peptide and oxidatively modified lipids in idiopathic autism and dup(15q11.2-q13)/autism
Frackowiak J, Mazur-Kolecka B, Schanen N, Brown W, Wegiel J
Acta Neuropathologica Communications 2013, 1:61 (16 September 2013)
Abstract http://www.actaneurocomms.org/content/1/1/61/abstract
Full text http://www.actaneurocomms.org/content/1/1/61
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-61.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252310

Review
Distinct origins of dura mater graft-associated Creutzfeldt-Jakob disease: past and future problems
Kobayashi A, Matsuura Y, Mohri S, Kitamoto T
Acta Neuropathologica Communications 2014, 2:32 (31 March 2014)
Abstract http://www.actaneurocomms.org/content/2/1/32/abstract
Full text http://www.actaneurocomms.org/content/2/1/32
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-32.pdf
PubMed http://www.actaneurocomms.org/pubmed/24685293

Review
Lipid dysfunction and pathogenesis of multiple system atrophy
Bleasel JM, Wong JH, Halliday GM, Kim W
Acta Neuropathologica Communications 2014, 2:15 (7 February 2014)
Abstract http://www.actaneurocomms.org/content/2/1/15/abstract
Full text http://www.actaneurocomms.org/content/2/1/15
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-2-15.pdf
PubMed http://www.actaneurocomms.org/pubmed/24502382

Review
Molecular chaperones and protein folding as therapeutic targets in Parkinson’s disease and other synucleinopathies
Ebrahimi-Fakhari D, Saidi L, Wahlster L
Acta Neuropathologica Communications 2013, 1:79 (5 December 2013)
Abstract http://www.actaneurocomms.org/content/1/1/79/abstract
Full text http://www.actaneurocomms.org/content/1/1/79
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-79.pdf
PubMed http://www.actaneurocomms.org/pubmed/24314025

Review
The airbag problem–a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer’s disease
Krstic D, Knuesel I
Acta Neuropathologica Communications 2013, 1:62 (23 September 2013)
Abstract http://www.actaneurocomms.org/content/1/1/62/abstract
Full text http://www.actaneurocomms.org/content/1/1/62
PDF http://www.actaneurocomms.org/content/pdf/2051-5960-1-62.pdf
PubMed http://www.actaneurocomms.org/pubmed/24252346








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